AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
An investigation into the nuclear events involved in autophagy regulation identifies the histone arginine methyltransferase CARM1 as a transcriptional co-activator of transcription factor TFEB; CARM1 levels are decreased by the SKP2-containing E3 ubiquitin ligase and increased during autophagy induction after nutrient starvation.
Autophagy induc...
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Full title
AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5568428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5568428
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature18014