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AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5568428

AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

About this item

Full title

AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2016-06, Vol.534 (7608), p.553-557

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

An investigation into the nuclear events involved in autophagy regulation identifies the histone arginine methyltransferase CARM1 as a transcriptional co-activator of transcription factor TFEB; CARM1 levels are decreased by the SKP2-containing E3 ubiquitin ligase and increased during autophagy induction after nutrient starvation.
Autophagy induc...

Alternative Titles

Full title

AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5568428

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5568428

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature18014

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