Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Bi...
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Gil McVean and colleagues present a new Bayesian analysis framework that exploits the hierarchical structure of diagnosis classifications to analyze genetic variants against UK Biobank disease phenotypes derived from self-reporting and hospital episode statistics. Their method displays increased power to detect genetic effects over other approaches...
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Full title
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5580804
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5580804
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3926
