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Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cel...

Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5582213

Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells

About this item

Full title

Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2017-08, Vol.36 (34), p.4887-4900

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond. Intriguingly, formation of giant cells due to failed mitosis/cytok...

Alternative Titles

Full title

Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5582213

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5582213

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2017.72

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