Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Thymic regulatory T (T
reg
) precursors undergo a distinct developmental pathway. Sakaguchi and colleagues show the chromatin organizer Satb1 is required for establishing the super-enhancer chromatin landscape of T
reg
cell–specific signature genes before
Foxp3
expression.
Most Foxp3
+
regulatory T (T
reg
) cells de...
Alternative Titles
Full title
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5582804
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5582804
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3646
