Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells in vitro...
Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells in vitro and in vivo
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Publisher
Greece: D.A. Spandidos
Journal title
Language
English
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Publication information
Publisher
Greece: D.A. Spandidos
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Scope and Contents
Contents
Gimeracil or 5-chloro-2,4-dihydroxypyridine (CDHP) enhances the antitumor effects of 5-fluorouracil (5-FU) by inhibiting dihydropyrimidine dehydrogenase (DPD), which is involved in the degradation of 5-FU. CDHP, as part of a combination therapy, was also reported to exert a radiosensitizing effect. Therefore, CDHP may have underlying mechanisms of...
Alternative Titles
Full title
Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells in vitro and in vivo
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5587992
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5587992
Other Identifiers
ISSN
1792-1074
E-ISSN
1792-1082
DOI
10.3892/ol.2017.6602
