Recombination initiation maps of individual human genomes
Recombination initiation maps of individual human genomes
About this item
Full title
Author / Creator
Publisher
Washington: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington: American Association for the Advancement of Science
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More information
Scope and Contents
Contents
DNA double-strand breaks (DSBs) are introduced in meiosis to initiate recombination and generate crossovers, the reciprocal exchanges of genetic material between parental chromosomes. Here, we present high-resolution maps of meiotic DSBs in individual human genomes. Comparing DSB maps between individuals shows that along with DNA binding by PRDM9,...
Alternative Titles
Full title
Recombination initiation maps of individual human genomes
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5588152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5588152
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1256442
