Spironolactone Metabolites in TOPCAT — New Insights into Regional Variation
Spironolactone Metabolites in TOPCAT — New Insights into Regional Variation
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Publisher
United States: Massachusetts Medical Society
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Language
English
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Publisher
United States: Massachusetts Medical Society
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Contents
In a subgroup of TOPCAT participants assigned to spironolactone, the spironolactone metabolite canrenone was measured to assess adherence. Canrenone levels were undetectable in 30% of participants from Russia, as compared with only 3% from the United States and Canada.
To the Editor:
In the Treatment of Preserved Cardiac Function Heart Failur...
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Full title
Spironolactone Metabolites in TOPCAT — New Insights into Regional Variation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5590224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5590224
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMc1612601
