Wu-Mei-Wan Reduces Insulin Resistance via Inhibition of NLRP3 Inflammasome Activation in HepG2 Cells
Wu-Mei-Wan Reduces Insulin Resistance via Inhibition of NLRP3 Inflammasome Activation in HepG2 Cells
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Author / Creator
Chen, Guang , Lu, Fuer , Huang, Zhaoyi , Dong, Hui , Zhao, Yan , Li, Jingbin , Dong, Ruolan , Fang, Ke , Li, Lingli , Yang, Xueping and Yi, Ping
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
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Publication information
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Scope and Contents
Contents
Wu-Mei-Wan (WMW) is a Chinese herbal formula used to treat type 2 diabetes. In this study, we aimed to explore the effects and mechanisms of WMW on insulin resistance in HepG2 cells. HepG2 cells were pretreated with palmitate (0.25 mM) to impair the insulin signaling pathway. Then, they were treated with different doses of WMW-containing medicated...
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Full title
Wu-Mei-Wan Reduces Insulin Resistance via Inhibition of NLRP3 Inflammasome Activation in HepG2 Cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5591966
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5591966
Other Identifiers
ISSN
1741-427X
E-ISSN
1741-4288
DOI
10.1155/2017/7283241