Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G
Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G
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Author / Creator
Emptoz, Alice , Michel, Vincent , Lelli, Andrea , Akil, Omar , de Monvel, Jacques Boutet , Lahlou, Ghizlene , Meyer, Anaïs , Dupont, Typhaine , Nouaille, Sylvie , Ey, Elody , de Barros, Filipa Franca , Beraneck, Mathieu , Dulon, Didier , Hardelin, Jean-Pierre , Lustig, Lawrence , Avan, Paul , Petit, Christine and Safieddine, Saaid
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Our understanding of the mechanisms underlying inherited forms of inner ear deficits has considerably improved during the past 20 y, but we are still far from curative treatments. We investigated gene replacement as a strategy for restoring inner ear functions in a mouse model of Usher syndrome type 1G, characterized by congenital profound deafness...
Alternative Titles
Full title
Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5594693
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5594693
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1708894114
