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Epithelial expression and function of trypsin-3 in irritable bowel syndrome

Epithelial expression and function of trypsin-3 in irritable bowel syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595105

Epithelial expression and function of trypsin-3 in irritable bowel syndrome

About this item

Full title

Epithelial expression and function of trypsin-3 in irritable bowel syndrome

Publisher

England: BMJ Publishing Group LTD

Journal title

Gut, 2017-10, Vol.66 (10), p.1767-1778

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

ObjectivesProteases are key mediators of pain and altered enteric neuronal signalling, although the types and sources of these important intestinal mediators are unknown. We hypothesised that intestinal epithelium is a major source of trypsin-like activity in patients with IBS and this activity signals to primary afferent and enteric nerves and ind...

Alternative Titles

Full title

Epithelial expression and function of trypsin-3 in irritable bowel syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595105

Other Identifiers

ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2016-312094

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