Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers
Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Summary
Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue from 26 subjects aged 18–88 years to investigate changes in expression of six genes representing different stages of neurogenesis across the healthy adult lifespan....
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Full title
Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595679
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595679
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ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12641