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Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595679

Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

About this item

Full title

Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2017-10, Vol.16 (5), p.1195-1199

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Summary
Reduced neurogenesis in the aging mammalian hippocampus has been linked to cognitive deficits and increased risk of dementia. We utilized postmortem human hippocampal tissue from 26 subjects aged 18–88 years to investigate changes in expression of six genes representing different stages of neurogenesis across the healthy adult lifespan....

Alternative Titles

Full title

Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595679

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5595679

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.12641

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