Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
About this item
Full title
Author / Creator
van der Weyden, Louise , Arends, Mark J. , Campbell, Andrew D. , Bald, Tobias , Wardle-Jones, Hannah , Griggs, Nicola , Velasco-Herrera, Martin Del Castillo , Tüting, Thomas , Sansom, Owen J. , Karp, Natasha A. , Clare, Simon , Gleeson, Diane , Ryder, Edward , Galli, Antonella , Tuck, Elizabeth , Cambridge, Emma L. , Voet, Thierry , Macaulay, Iain C. , Wong, Kim , Spiegel, Sarah , Speak, Anneliese O. , Adams, David J. and Sanger Mouse Genetics Project
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Screening mutant mouse lines using a genome-wide
in vivo
assay identifies microenvironmental regulators of metastatic colonization and defines SPNS2 as an important mediator of lung colonization.
SPNS2 protein regulates metastasis
The multistep process of the metastastic colonization of tumours is influenced by the tissue and systemic m...
Alternative Titles
Full title
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
Authors, Artists and Contributors
Author / Creator
Arends, Mark J.
Campbell, Andrew D.
Bald, Tobias
Wardle-Jones, Hannah
Griggs, Nicola
Velasco-Herrera, Martin Del Castillo
Tüting, Thomas
Sansom, Owen J.
Karp, Natasha A.
Clare, Simon
Gleeson, Diane
Ryder, Edward
Galli, Antonella
Tuck, Elizabeth
Cambridge, Emma L.
Voet, Thierry
Macaulay, Iain C.
Wong, Kim
Spiegel, Sarah
Speak, Anneliese O.
Adams, David J.
Sanger Mouse Genetics Project
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603286
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603286
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature20792