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Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603286

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

About this item

Full title

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-01, Vol.541 (7636), p.233-236

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Screening mutant mouse lines using a genome-wide
in vivo
assay identifies microenvironmental regulators of metastatic colonization and defines SPNS2 as an important mediator of lung colonization.
SPNS2 protein regulates metastasis
The multistep process of the metastastic colonization of tumours is influenced by the tissue and systemic m...

Alternative Titles

Full title

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603286

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603286

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature20792

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