Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC
About this item
Full title
Author / Creator
Satoh, Kiyotoshi , Yachida, Shinichi , Sugimoto, Masahiro , Oshima, Minoru , Nakagawa, Toshitaka , Akamoto, Shintaro , Tabata, Sho , Saitoh, Kaori , Kato, Keiko , Sato, Saya , Igarashi, Kaori , Aizawa, Yumi , Kajino-Sakamoto, Rie , Kojima, Yasushi , Fujishita, Teruaki , Enomoto, Ayame , Hirayama, Akiyoshi , Ishikawa, Takamasa , Taketo, Makoto Mark , Kushida, Yoshio , Haba, Reiji , Okano, Keiichi , Tomita, Masaru , Suzuki, Yasuyuki , Fukuda, Shinji , Aoki, Masahiro and Soga, Tomoyoshi
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cancer cells alter their metabolism for the production of precursors of macromolecules. However, the control mechanisms underlying this reprogramming are poorly understood. Here we show that metabolic reprogramming of colorectal cancer is caused chiefly by aberrant MYC expression. Multiomics-based analyses of paired normal and tumor tissues from 27...
Alternative Titles
Full title
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC
Authors, Artists and Contributors
Author / Creator
Yachida, Shinichi
Sugimoto, Masahiro
Oshima, Minoru
Nakagawa, Toshitaka
Akamoto, Shintaro
Tabata, Sho
Saitoh, Kaori
Kato, Keiko
Sato, Saya
Igarashi, Kaori
Aizawa, Yumi
Kajino-Sakamoto, Rie
Kojima, Yasushi
Fujishita, Teruaki
Enomoto, Ayame
Hirayama, Akiyoshi
Ishikawa, Takamasa
Taketo, Makoto Mark
Kushida, Yoshio
Haba, Reiji
Okano, Keiichi
Tomita, Masaru
Suzuki, Yasuyuki
Fukuda, Shinji
Aoki, Masahiro
Soga, Tomoyoshi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5604037
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5604037
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1710366114
