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Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating...

Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5614914

Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway

About this item

Full title

Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-09, Vol.7 (1), p.12302-11, Article 12302

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Astragaloside II (AS II) extracted from
Astragalus membranaceus
has been reported to promote tissue wound repair. However, the effect of AS II on inflammatory bowel disease is unknown. We investigated the effects and mechanism of AS II on intestinal wound healing in both
in vitro
and
in vivo
models. Human intestinal Caco-2 cells w...

Alternative Titles

Full title

Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5614914

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5614914

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-12435-y

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