Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L...
Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels
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Publisher
National Academy of Sciences
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Language
English
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National Academy of Sciences
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Fast neurotransmitter release from ribbon synapses via Ca2+-triggered exocytosis requires tight coupling of L-type Ca2+ channels to release-ready synaptic vesicles at the presynaptic active zone, which is localized at the base of the ribbon. Here, we used genetic, electrophysiological, and ultrastructural analyses to probe the architecture of ribbo...
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Full title
Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617259
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617259
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1702991114
