Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine recept...
Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Venom peptide toxins such as conotoxins play a critical role in the characterization of nicotinic acetylcholine receptor (nAChR) structure and function and have potential as nervous system therapeutics as well. However, the lack of solved structures of conotoxins bound to nAChRs and the large size of these peptides are barriers to their computation...
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Full title
Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617267
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1703952114