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Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine recept...

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine recept...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617267

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models

About this item

Full title

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (38), p.E8100-E8109

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Venom peptide toxins such as conotoxins play a critical role in the characterization of nicotinic acetylcholine receptor (nAChR) structure and function and have potential as nervous system therapeutics as well. However, the lack of solved structures of conotoxins bound to nAChRs and the large size of these peptides are barriers to their computation...

Alternative Titles

Full title

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617267

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5617267

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1703952114

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