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The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5618535

The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

About this item

Full title

The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2017-08, Vol.18 (9), p.1886

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The deoxyribonucleic acid (DNA) damage response (DDR) is a major feature in the maintenance of genome integrity and in the suppression of tumorigenesis. PALB2 (Partner and Localizer of Breast Cancer 2 (BRCA2)) plays an important role in maintaining genome integrity through its role in the Fanconi anemia (FA) and homologous recombination (HR) DNA re...

Alternative Titles

Full title

The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5618535

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5618535

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms18091886

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