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Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma

Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5619018

Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma

About this item

Full title

Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma

Publisher

London: Future Medicine Ltd

Journal title

Immunotherapy, 2016-03, Vol.8 (3), p.299-313

Language

English

Formats

Publication information

Publisher

London: Future Medicine Ltd

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC) is a fatal disease with rising incidence in the world. For advanced HCC, sorafenib, a multikinase inhibitor, is the only systemic therapy with proven survival benefits. Sorafenib is a pan-VEGF receptor inhibitor, and thus many studies have focused its antivascular effects. But VEGF also acts as an immunosuppressive mo...

Alternative Titles

Full title

Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5619018

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5619018

Other Identifiers

ISSN

1750-743X

E-ISSN

1750-7448

DOI

10.2217/imt.15.126

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