T cells of Parkinson’s disease patients recognize α–synuclein peptides
T cells of Parkinson’s disease patients recognize α–synuclein peptides
About this item
Full title
Author / Creator
Sulzer, David , Alcalay, Roy N. , Garretti, Francesca , Cote, Lucien , Kanter, Ellen , Agin-Liebes, Julian P. , Liong, Christopher , McMurtrey, Curtis , Hildebrand, William H. , Mao, Xiaobo , Dawson, Valina L. , Dawson, Ted M. , Oseroff, Carla , Pham, John , Sidney, John , Dillon, Myles B , Carpenter, Chelsea , Weiskopf, Daniela , Phillips, Elizabeth , Mallal, Simon , Peters, Bjoern , Frazier, April , Lindestam Arlehamn, Cecilia S. and Sette, Alessandro
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
Genetic studies associate Parkinson’s disease with alleles of the major histocompatibility complex
1
–
3
. We find that a defined set of peptides derived from α-synuclein, a protein aggregated in Parkinson’s disease
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, act as antigenic epitopes displayed by these alleles and drive helper and cytotoxic T cell responses in Parkinso...
Alternative Titles
Full title
T cells of Parkinson’s disease patients recognize α–synuclein peptides
Authors, Artists and Contributors
Author / Creator
Alcalay, Roy N.
Garretti, Francesca
Cote, Lucien
Kanter, Ellen
Agin-Liebes, Julian P.
Liong, Christopher
McMurtrey, Curtis
Hildebrand, William H.
Mao, Xiaobo
Dawson, Valina L.
Dawson, Ted M.
Oseroff, Carla
Pham, John
Sidney, John
Dillon, Myles B
Carpenter, Chelsea
Weiskopf, Daniela
Phillips, Elizabeth
Mallal, Simon
Peters, Bjoern
Frazier, April
Lindestam Arlehamn, Cecilia S.
Sette, Alessandro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5626019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5626019
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22815
