Insulin Receptor Isoforms in Physiology and Disease: An Updated View
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
About this item
Full title
Author / Creator
Publisher
Washington, DC: Endocrine Society
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: Endocrine Society
Subjects
More information
Scope and Contents
Contents
The insulin receptor (IR) gene undergoes differential splicing that generates two IR isoforms, IR-A and IR-B. The physiological roles of IR isoforms are incompletely understood and appear to be determined by their different binding affinities for insulin-like growth factors (IGFs), particularly for IGF-2. Predominant roles of IR-A in prenatal growt...
Alternative Titles
Full title
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5629070
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5629070
Other Identifiers
ISSN
0163-769X
E-ISSN
1945-7189
DOI
10.1210/er.2017-00073
