A Phase I Study of Combination Therapy with Sorafenib and 5-Fluorouracil in Patients with Advanced H...
A Phase I Study of Combination Therapy with Sorafenib and 5-Fluorouracil in Patients with Advanced Hepatocellular Carcinoma
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Author / Creator
Sho, Takuya , Nakanishi, Mitsuru , Morikawa, Kenichi , Ohara, Masatsugu , Kawagishi, Naoki , Izumi, Takaaki , Umemura, Machiko , Ito, Jun , Nakai, Masato , Suda, Goki , Ogawa, Koji , Chuma, Makoto , Meguro, Takashi , Nakamura, Michio , Nagasaka, Atsushi , Horimoto, Hiromasa , Yamamoto, Yoshiya and Sakamoto, Naoya
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Background and aims
Sorafenib is the first molecular targeted drug approved for the treatment of advanced hepatocellular carcinoma (HCC) and is a potent small molecule inhibitor of multiple kinases. Combination therapy with sorafenib and other cytotoxic agents for HCC may result in additive anticancer activity. The purpose of this phase I study...
Alternative Titles
Full title
A Phase I Study of Combination Therapy with Sorafenib and 5-Fluorouracil in Patients with Advanced Hepatocellular Carcinoma
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5629128
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5629128
Other Identifiers
ISSN
1174-5886
E-ISSN
1179-6901
DOI
10.1007/s40268-017-0187-7