Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric a...
Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pseudolaric acid B （PAB）, a diterpene acid isolated from the root bark of Pseudolarix kaempferi Gordon, exerts anti-tumor effects in several cancer cell lines. Our previous study showed that PAB mainly induced senescence via p53-p21 activation rather than apoptosis in suppression of the growth of human lung cancer A549 cells （p53 wild-type）. In p53...
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Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5630671
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5630671
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1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2017.39
