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Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5630681

Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

About this item

Full title

Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Cell research, 2017-10, Vol.27 (10), p.1216-1230

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Spermatogenesis is a differentiation process during which diploid spermatogonial stem cells (SSCs) produce hap- loid spermatozoa. This highly specialized process is precisely controlled at the transcriptional, posttranscriptional, and translational levels. Here we report that N6-methyladenosine (m6A), an epitranscriptomic mark regulating gene expre...

Alternative Titles

Full title

Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5630681

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5630681

Other Identifiers

ISSN

1001-0602

E-ISSN

1748-7838

DOI

10.1038/cr.2017.117

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