P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression
P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression
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US: Oxford University Press
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English
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US: Oxford University Press
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BackgroundMajor depressive disorder is characterized by structural and functional abnormalities of cortical and limbic brain areas, including a decrease in spine synapse number in the dentate gyrus of the hippocampus. Recent studies highlighted that both genetic and pharmacological invalidation of the purinergic P2X7 receptor (P2rx7) leads to antid...
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P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5632310
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5632310
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1461-1457
E-ISSN
1469-5111
DOI
10.1093/ijnp/pyx046