Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an...
Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression
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Author / Creator
Esterlis, I , DellaGioia, N , Pietrzak, R H , Matuskey, D , Nabulsi, N , Abdallah, C G , Yang, J , Pittenger, C , Sanacora, G , Krystal, J H , Parsey, R V , Carson, R E and DeLorenzo, C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The mechanisms of action of the rapid antidepressant effects of ketamine, an
N
-methyl-
D
-aspartate glutamate receptor antagonist, have not been fully elucidated. This study examined the effects of ketamine on ligand binding to a metabotropic glutamatergic receptor (mGluR5) in individuals with major depressive disorder (MDD) and health...
Alternative Titles
Full title
Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5636649
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5636649
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/mp.2017.58
