The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical ca...
The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical cancer
About this item
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Author / Creator
Publisher
Greece: Spandidos Publications UK Ltd
Journal title
Language
English
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Publication information
Publisher
Greece: Spandidos Publications UK Ltd
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Scope and Contents
Contents
High-risk human papilloma virus (HPV) is the leading cause of cervical cancer. HPV oncogenes are responsible for the development of malignancy, and the E6 oncoprotein that HPV expresses induces the degradation of tumour suppressor protein p53 (p53). This degradation leads to the upregulation of p16; however, unidentified proteins may also serve a r...
Alternative Titles
Full title
The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical cancer
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5649573
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5649573
Other Identifiers
ISSN
1792-1074
E-ISSN
1792-1082
DOI
10.3892/ol.2017.6752
