Blocking FSH induces thermogenic adipose tissue and reduces body fat
Blocking FSH induces thermogenic adipose tissue and reduces body fat
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Author / Creator
Liu, Peng , Ji, Yaoting , Yuen, Tony , Rendina-Ruedy, Elizabeth , DeMambro, Victoria E. , Dhawan, Samarth , Abu-Amer, Wahid , Izadmehr, Sudeh , Zhou, Bin , Shin, Andrew C. , Latif, Rauf , Thangeswaran, Priyanthan , Gupta, Animesh , Li, Jianhua , Shnayder, Valeria , Robinson, Samuel T. , Yu, Yue Eric , Zhang, Xingjian , Yang, Feiran , Lu, Ping , Zhou, Yu , Zhu, Ling-Ling , Oberlin, Douglas J. , Davies, Terry F. , Reagan, Michaela R. , Brown, Aaron , Kumar, T. Rajendra , Epstein, Solomon , Iqbal, Jameel , Avadhani, Narayan G. , New, Maria I. , Molina, Henrik , van Klinken, Jan B. , Guo, Edward X. , Buettner, Christoph , Haider, Shozeb , Bian, Zhuan , Sun, Li , Rosen, Clifford J. and Zaidi, Mone
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Menopause is associated with bone loss and enhanced visceral adiposity. A polyclonal antibody that targets the β-subunit of the pituitary hormone follicle-stimulating hormone (Fsh) increases bone mass in mice. Here, we report that this antibody sharply reduces adipose tissue in wild-type mice, phenocopying genetic haploinsufficiency for the Fsh rec...
Alternative Titles
Full title
Blocking FSH induces thermogenic adipose tissue and reduces body fat
Authors, Artists and Contributors
Author / Creator
Ji, Yaoting
Yuen, Tony
Rendina-Ruedy, Elizabeth
DeMambro, Victoria E.
Dhawan, Samarth
Abu-Amer, Wahid
Izadmehr, Sudeh
Zhou, Bin
Shin, Andrew C.
Latif, Rauf
Thangeswaran, Priyanthan
Gupta, Animesh
Li, Jianhua
Shnayder, Valeria
Robinson, Samuel T.
Yu, Yue Eric
Zhang, Xingjian
Yang, Feiran
Lu, Ping
Zhou, Yu
Zhu, Ling-Ling
Oberlin, Douglas J.
Davies, Terry F.
Reagan, Michaela R.
Brown, Aaron
Kumar, T. Rajendra
Epstein, Solomon
Iqbal, Jameel
Avadhani, Narayan G.
New, Maria I.
Molina, Henrik
van Klinken, Jan B.
Guo, Edward X.
Buettner, Christoph
Haider, Shozeb
Bian, Zhuan
Sun, Li
Rosen, Clifford J.
Zaidi, Mone
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5651981
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5651981
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22342
