Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Both F17-like and type 1 pili promote intestinal colonization in mouse colonic crypts, and the high-affinity mannoside M4284 reduces intestinal colonization of uropathogenic
Escherichia coli
while simultaneously treating urinary tract infections without disrupting the composition of the gut microbiota.
UTI reduction by mannoside
Uropath...
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Full title
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5654549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5654549
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature22972