Lactate dehydrogenase activity drives hair follicle stem cell activation
Lactate dehydrogenase activity drives hair follicle stem cell activation
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Author / Creator
Flores, Aimee , Schell, John , Krall, Abigail S. , Jelinek, David , Miranda, Matilde , Grigorian, Melina , Braas, Daniel , White, Andrew C. , Zhou, Jessica L. , Graham, Nicholas A. , Graeber, Thomas , Seth, Pankaj , Evseenko, Denis , Coller, Hilary A. , Rutter, Jared , Christofk, Heather R. and Lowry, William E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Although normally dormant, hair follicle stem cells (HFSCs) quickly become activated to divide during a new hair cycle. The quiescence of HFSCs is known to be regulated by a number of intrinsic and extrinsic mechanisms. Here we provide several lines of evidence to demonstrate that HFSCs utilize glycolytic metabolism and produce significantly more l...
Alternative Titles
Full title
Lactate dehydrogenase activity drives hair follicle stem cell activation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5657543
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5657543
Other Identifiers
ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/ncb3575