Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantat...
Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
While heart transplantation (HTX) is the definitive therapy of heart failure, donor shortage is emerging. Pharmacological activation of soluble guanylate cyclase (sGC) and increased cGMP-signalling have been reported to have cardioprotective properties. Gemfibrozil has recently been shown to exert sGC activating effects
in vitro
. We aimed to...
Alternative Titles
Full title
Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5660179
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5660179
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-14587-3
