TDP-43 accelerates age-dependent degeneration of interneurons
TDP-43 accelerates age-dependent degeneration of interneurons
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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TDP-43 is an RNA-binding protein important for many aspects of RNA metabolism. Abnormal accumulation of TDP-43 in the cytoplasm of affected neurons is a pathological hallmark of the neurodegenerative diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Several transgenic mouse models have been generated that recapitulate...
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TDP-43 accelerates age-dependent degeneration of interneurons
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5668320
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5668320
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-14966-w
