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Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5669557

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

About this item

Full title

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2017-09, Vol.127 (9), p.3510-3520

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

In response to injury, epithelial cells migrate and proliferate to cover denuded mucosal surfaces and repair the barrier defect. This process is orchestrated by dynamic crosstalk between immune cells and the epithelium; however, the mechanisms involved remain incompletely understood. Here, we report that IL-10 was rapidly induced following intestin...

Alternative Titles

Full title

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5669557

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5669557

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI90229

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