SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling
SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Background:
Overexpression of epidermal growth factor receptor (EGFR) occurs in approximately 90% of head and neck squamous cell carcinoma (HNSCC), and is correlated with poor prognosis. Thus, targeting EGFR is a promising strategy for treatment of HNSCC. Several small molecule EGFR inhibitors have been tested in clinical trials for treatment of...
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SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674107
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674107
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2017.298