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SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674107

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

About this item

Full title

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2017-10, Vol.117 (8), p.1154-1163

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Background:
Overexpression of epidermal growth factor receptor (EGFR) occurs in approximately 90% of head and neck squamous cell carcinoma (HNSCC), and is correlated with poor prognosis. Thus, targeting EGFR is a promising strategy for treatment of HNSCC. Several small molecule EGFR inhibitors have been tested in clinical trials for treatment of...

Alternative Titles

Full title

SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5674107

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/bjc.2017.298

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