WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
About this item
Full title
Author / Creator
Kannan, Meghna , Bayam, Efil , Wagner, Christel , Rinaldi, Bruno , Kretz, Perrine F. , Tilly, Peggy , Roos, Marna , McGillewie, Lara , Bär, Séverine , Minocha, Shilpi , Chevalier, Claire , Po, Chrystelle , Project, Sanger Mouse Genetics , Chelly, Jamel , Mandel, Jean-Louis , Borgatti, Renato , Piton, Amélie , Kinnear, Craig , Loos, Ben , Adams, David J. , Hérault, Yann , Collins, Stephan C. , Friant, Sylvie , Godin, Juliette D. , Yalcin, Binnaz and Sanger Mouse Genetics Project
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The family of WD40-repeat (WDR) proteins is one of the largest in eukaryotes, but little is known about their function in brain development. Among 26 WDR genes assessed, we found 7 displaying a major impact in neuronal morphology when inactivated in mice. Remarkably, all seven genes showed corpus callosum defects, including thicker (Atg16l1, Coro1c...
Alternative Titles
Full title
WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
Authors, Artists and Contributors
Author / Creator
Bayam, Efil
Wagner, Christel
Rinaldi, Bruno
Kretz, Perrine F.
Tilly, Peggy
Roos, Marna
McGillewie, Lara
Bär, Séverine
Minocha, Shilpi
Chevalier, Claire
Po, Chrystelle
Project, Sanger Mouse Genetics
Chelly, Jamel
Mandel, Jean-Louis
Borgatti, Renato
Piton, Amélie
Kinnear, Craig
Loos, Ben
Adams, David J.
Hérault, Yann
Collins, Stephan C.
Friant, Sylvie
Godin, Juliette D.
Yalcin, Binnaz
Sanger Mouse Genetics Project
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5676932
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5676932
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1713625114
