Mnt modulates Myc-driven lymphomagenesis
Mnt modulates Myc-driven lymphomagenesis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The transcriptional represser Mnt is a functional antagonist of the proto-oncoprotein Myc. Both Mnt and Myc utilise Max as an obligate partner for DNA binding, and Myc/Max and Mnt/Max complexes compete for occupancy at E-box DNA sequences in promoter regions. We have previously shown in transgenic mouse models that the phenotype and kinetics of ons...
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Full title
Mnt modulates Myc-driven lymphomagenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5686348
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5686348
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2017.131
