miR-148a inhibits colitis and colitis-associated tumorigenesis in mice
miR-148a inhibits colitis and colitis-associated tumorigenesis in mice
About this item
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Author / Creator
Zhu, Yahui , Gu, Li , Li, Yajun , Lin, Xi , Shen, Hongxing , Cui, Kaisa , Chen, Li , Zhou, Feng , Zhao, Qiu , Zhang, Jinxiang , Zhong, Bo , Prochownik, Edward and Li, Youjun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
miR-148a has been shown to regulate inflammation, immunity and the growth of certain tumors, but its roles in colitis and colorectal tumorigenesis remain largely undetermined. Here we found miR-148a-deficient mice to be more susceptible to colitis and colitis-associated tumorigenesis. Both were associated with increased nuclear factor
κ
B (NF...
Alternative Titles
Full title
miR-148a inhibits colitis and colitis-associated tumorigenesis in mice
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5686357
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5686357
Other Identifiers
ISSN
1350-9047,1476-5403
E-ISSN
1476-5403
DOI
10.1038/cdd.2017.151
