Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release
Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In the gastrointestinal (GI) epithelium, enterochromaffin (EC) cells are enteroendocrine cells responsible for producing >90% of the body’s serotonin (5-hydroxytryptamine, 5-HT). However, the molecular mechanisms of EC cell function are poorly understood. Here, we found that EC cells in mouse primary cultures fired spontaneous bursts of action pote...
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Full title
Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5688111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5688111
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-15834-3
