Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of g...
Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model
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Author / Creator
Qu, Youge , Yang, Chun , Ren, Qian , Ma, Min , Dong, Chao and Hashimoto, Kenji
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Accumulating evidence suggests a key role of the gut–microbiota–brain axis in the antidepressant actions of certain compounds. Ketamine, an
N
-methyl-D-aspartate receptor (NMDAR) antagonist, showed rapid and sustained antidepressant effects in treatment-resistant depressed patients. In contrast, another NMDAR antagonist, lanicemine, did not e...
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Full title
Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5691133
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5691133
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-16060-7
