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Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5696472

Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

About this item

Full title

Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-11, Vol.7 (1), p.15840-12, Article 15840

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glioblastoma stem-like cells (GSC) are hypothesized to evade current therapies and cause tumor recurrence, contributing to poor patient survival. Existing cell surface markers for GSC are developed from embryonic or neural stem cell systems; however, currently available GSC markers are suboptimal in sensitivity and specificity. We hypothesized that...

Alternative Titles

Full title

Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5696472

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5696472

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-16066-1

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