The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
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Author / Creator
Lynes, Matthew D , Leiria, Luiz O , Lundh, Morten , Bartelt, Alexander , Shamsi, Farnaz , Huang, Tian Lian , Takahashi, Hirokazu , Hirshman, Michael F , Schlein, Christian , Lee, Alexandra , Baer, Lisa A , May, Francis J , Gao, Fei , Narain, Niven R , Chen, Emily Y , Kiebish, Michael A , Cypess, Aaron M , Blüher, Matthias , Goodyear, Laurie J , Hotamisligil, Gökhan S , Stanford, Kristin I and Tseng, Yu-Hua
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Cold stimulation induces the synthesis and release of the lipid species 12,13-diHOME from brown adipose tissue. This ‘lipokine’ then acts on brown adipocytes to promote the uptake of fatty acids to fuel this cell type's heat production.
Brown adipose tissue (BAT) and beige adipose tissue combust fuels for heat production in adult humans, and so...
Alternative Titles
Full title
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
Authors, Artists and Contributors
Author / Creator
Leiria, Luiz O
Lundh, Morten
Bartelt, Alexander
Shamsi, Farnaz
Huang, Tian Lian
Takahashi, Hirokazu
Hirshman, Michael F
Schlein, Christian
Lee, Alexandra
Baer, Lisa A
May, Francis J
Gao, Fei
Narain, Niven R
Chen, Emily Y
Kiebish, Michael A
Cypess, Aaron M
Blüher, Matthias
Goodyear, Laurie J
Hotamisligil, Gökhan S
Stanford, Kristin I
Tseng, Yu-Hua
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5699924
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5699924
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4297
