Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activ...
Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Metformin is a widely used and well-tolerated anti-diabetic drug that can reduce cancer risk and improve the prognosis of certain malignancies. However, the mechanism underlying its anti-cancer effect is still unclear. We studied the anti-cancer activity of metformin on colorectal cancer (CRC) by using the drug to treat HT29, HCT116 and HCT116 p53−...
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Full title
Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5700100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5700100
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-16149-z
