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The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pa...

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5701182

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

About this item

Full title

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-11, Vol.7 (1), p.16275-12, Article 16275

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

While amyloid-β protein (Aβ) aggregation into insoluble plaques is one of the pathological hallmarks of Alzheimer’s disease (AD), soluble oligomeric Aβ has been hypothesized to be responsible for synapse damage, neurodegeneration, learning, and memory deficits in AD. Here, we investigate the
in vitro
and
in vivo
efficacy of the
d
...

Alternative Titles

Full title

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5701182

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5701182

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-16565-1

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