Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway
Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway
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Author / Creator
Shao, Zengwu , Jing, Doudou , Huang, Donghua , Liang, Hang , Wu, Wei , Deng, Xiangyu and Zheng, Dong
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Contents
Purpose. To explore the effect and possible mechanism of icariin, a prenylated flavonol glycoside derived from the Chinese herb Epimedium sagittatum that was applied to IL-1β pretreated human nucleus pulposus (NP) cells. Methods. Human NP cells were isolated from intervertebral discs of patients with scoliosis and lumbar spondylolisthesis. The cell...
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Full title
Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5702406
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5702406
Other Identifiers
ISSN
1741-427X
E-ISSN
1741-4288
DOI
10.1155/2017/2198323
