Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunctio...
Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Approximately 90% of alpha-synuclein (α-Synuclein) deposited in Lewy bodies is phosphorylated at serine 129 suggesting that the accumulation of phosphorylated α-Synuclein is critical in the pathogenesis of Parkinson’s disease. However,
in vivo
experiments addressing the role of phosphorylated α-Synuclein in the progression of Parkinson’s dise...
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Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5705684
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5705684
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-15813-8
