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IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5707351

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

About this item

Full title

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-11, Vol.7 (1), p.16547-11, Article 16547

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

IL-27 and IL-35 are heterodimeric cytokines, members of the IL-12 family and considered to have immunomodulatory properties. Their role during neuroinflammation had been investigated using mutant mice devoid of either one of their subunits or lacking components of their receptors, yielding conflicting results. We sought to understand the therapeuti...

Alternative Titles

Full title

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5707351

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5707351

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-16702-w

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