Development and validation of a clinical cancer genomic profiling test based on massively parallel D...
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
About this item
Full title
Author / Creator
Frampton, Garrett M , Fichtenholtz, Alex , Otto, Geoff A , Wang, Kai , Downing, Sean R , He, Jie , Schnall-Levin, Michael , White, Jared , Sanford, Eric M , An, Peter , Sun, James , Juhn, Frank , Brennan, Kristina , Iwanik, Kiel , Maillet, Ashley , Buell, Jamie , White, Emily , Zhao, Mandy , Balasubramanian, Sohail , Terzic, Selmira , Richards, Tina , Banning, Vera , Garcia, Lazaro , Mahoney, Kristen , Zwirko, Zac , Donahue, Amy , Beltran, Himisha , Mosquera, Juan Miguel , Rubin, Mark A , Dogan, Snjezana , Hedvat, Cyrus V , Berger, Michael F , Pusztai, Lajos , Lechner, Matthias , Boshoff, Chris , Jarosz, Mirna , Vietz, Christine , Parker, Alex , Miller, Vincent A , Ross, Jeffrey S , Curran, John , Cronin, Maureen T , Stephens, Philip J , Lipson, Doron and Yelensky, Roman
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Clinical tests that rely on next-generation sequencing to evaluate large numbers of cancer genes can be validated using pooled cell lines with known mutations.
As more clinically relevant cancer genes are identified, comprehensive diagnostic approaches are needed to match patients to therapies, raising the challenge of optimization and analytica...
Alternative Titles
Full title
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
Authors, Artists and Contributors
Author / Creator
Fichtenholtz, Alex
Otto, Geoff A
Wang, Kai
Downing, Sean R
He, Jie
Schnall-Levin, Michael
White, Jared
Sanford, Eric M
An, Peter
Sun, James
Juhn, Frank
Brennan, Kristina
Iwanik, Kiel
Maillet, Ashley
Buell, Jamie
White, Emily
Zhao, Mandy
Balasubramanian, Sohail
Terzic, Selmira
Richards, Tina
Banning, Vera
Garcia, Lazaro
Mahoney, Kristen
Zwirko, Zac
Donahue, Amy
Beltran, Himisha
Mosquera, Juan Miguel
Rubin, Mark A
Dogan, Snjezana
Hedvat, Cyrus V
Berger, Michael F
Pusztai, Lajos
Lechner, Matthias
Boshoff, Chris
Jarosz, Mirna
Vietz, Christine
Parker, Alex
Miller, Vincent A
Ross, Jeffrey S
Curran, John
Cronin, Maureen T
Stephens, Philip J
Lipson, Doron
Yelensky, Roman
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5710001
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5710001
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2696
