Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency
Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency
About this item
Full title
Author / Creator
Pena, Izabella A , Roussel, Yann , Daniel, Kate , Mongeon, Kevin , Johnstone, Devon , Weinschutz Mendes, Hellen , Bosma, Marjolein , Saxena, Vishal , Lepage, Nathalie , Chakraborty, Pranesh , Dyment, David A , van Karnebeek, Clara D M , Verhoeven-Duif, Nanda , Bui, Tuan Vu , Boycott, Kym M , Ekker, Marc and MacKenzie, Alex
Publisher
United States: Genetics Society of America
Journal title
Language
English
Formats
Publication information
Publisher
United States: Genetics Society of America
Subjects
More information
Scope and Contents
Contents
Pyridoxine-dependent epilepsy (PDE) is a severe neonatal seizure disorder and is here modeled in aldh7a1 -/- zebrafish. Mutant larvae display spontaneous..
Pyridoxine-dependent epilepsy (PDE) is a rare disease characterized by mutations in the lysine degradation gene ALDH7A1 leading to recurrent neonatal seizures, which are uniquely alleviated b...
Alternative Titles
Full title
Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5714462
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5714462
Other Identifiers
ISSN
1943-2631,0016-6731
E-ISSN
1943-2631
DOI
10.1534/genetics.117.300137
