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Pericytes impair capillary blood flow and motor function after chronic spinal cord injury

Pericytes impair capillary blood flow and motor function after chronic spinal cord injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5716958

Pericytes impair capillary blood flow and motor function after chronic spinal cord injury

About this item

Full title

Pericytes impair capillary blood flow and motor function after chronic spinal cord injury

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2017-06, Vol.23 (6), p.733-741

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

In rat models of spinal cord injury, the region of the spinal cord below the site of injury becomes hypoxic owing to inadequate blood flow. This effect on blood flow is due to increased production of neurotransmitters known as ‘trace amines,’ which act on pericytes to constrict blood vessels. Alleviation of hypoxia by hyperoxic breathing or inhibit...

Alternative Titles

Full title

Pericytes impair capillary blood flow and motor function after chronic spinal cord injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5716958

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5716958

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.4331

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