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The endoplasmic reticulum stress-autophagy pathway is involved in apelin-13-induced cardiomyocyte hy...

The endoplasmic reticulum stress-autophagy pathway is involved in apelin-13-induced cardiomyocyte hy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5719161

The endoplasmic reticulum stress-autophagy pathway is involved in apelin-13-induced cardiomyocyte hypertrophy in vitro

About this item

Full title

The endoplasmic reticulum stress-autophagy pathway is involved in apelin-13-induced cardiomyocyte hypertrophy in vitro

Publisher

London: Nature Publishing Group UK

Journal title

Acta pharmacologica Sinica, 2017-12, Vol.38 (12), p.1589-1600

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Apelin is the endogenous ligand for the G protein-coupled receptor APJ, and plays important roles in the cardiovascular system. Our previous studies showed that apelin-13 promotes the hypertrophy of H9c2 rat cardiomyocytes through the PI3K-autophagy pathway. The aim of this study was to explore what roles ER stress and autophagy played in apelin-13...

Alternative Titles

Full title

The endoplasmic reticulum stress-autophagy pathway is involved in apelin-13-induced cardiomyocyte hypertrophy in vitro

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5719161

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5719161

Other Identifiers

ISSN

1671-4083,1745-7254

E-ISSN

1745-7254

DOI

10.1038/aps.2017.97

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