Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3...
Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Dengue vaccine trials have revealed deficits in our understanding of the mechanisms of protective immunity, demonstrating a need to measure epitope-specific antibody responses against each DENV serotype. HmAb 5J7 binds to a complex, 3-monomer spanning quaternary epitope in the DENV3 envelope (E) protein, but it is unclear whether all interactions a...
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Full title
Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5719398
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5719398
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-17355-5
